BDBM13345 1-(5-tert-Butyl-2H-pyrazol-3-yl)-3-[4-chloro-3-(pyridin-3-yloxymethyl)-phenyl]urea::3-(3-tert-butyl-1H-pyrazol-5-yl)-1-{4-chloro-3-[(pyridin-3-yloxy)methyl]phenyl}urea::Pyridine derived fragment based inhibitor 10
SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)c(COc3cccnc3)c2)[nH]n1
InChI Key InChIKey=NTMADESEDXKNFZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 13345
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair