BDBM136424 US8865726, 55

SMILES Cc1cc(-c2nc[nH]n2)ccc1-c1cnn2ccc(N3C(=O)OC[C@@H]3C(C)C)nc12

InChI Key InChIKey=HHJIPYQCCREESX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136424   

TargetSerine/threonine-protein kinase mTOR(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 136424BDBM136424(US8865726, 55)
Affinity DataIC50: 19.2nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent