BDBM136432 US8865726, 63

SMILES O=C1OC(C(F)(F)F)CN1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1

InChI Key InChIKey=ZUCLXKUMLDPMJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136432   

TargetSerine/threonine-protein kinase mTOR(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 136432BDBM136432(US8865726, 63)
Affinity DataIC50: 56.7nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent