BDBM136446 US8865726, 77

SMILES O=C1OC[C@H](Cc2ccccc2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1

InChI Key InChIKey=BGJXMULJUXWUQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136446   

TargetSerine/threonine-protein kinase mTOR(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 136446BDBM136446(US8865726, 77)
Affinity DataIC50: 17.1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent