BDBM137084 US8871790, 152::US8871790, 480

SMILES Cc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1

InChI Key InChIKey=BBGOSBDSLYHMRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 137084   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 137084BDBM137084(US8871790, 480 | US8871790, 152 | US20250017938, C...)
Affinity DataIC50: 52nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 137084BDBM137084(US8871790, 480 | US8871790, 152 | US20250017938, C...)
Affinity DataIC50: 180nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 137084BDBM137084(US8871790, 480 | US8871790, 152 | US20250017938, C...)
Affinity DataIC50: 840nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent