BDBM138204 US8871778, 161

SMILES Cc1nn(cc1CN1CC(O)C1)-c1ccnc(Nc2ccc3n(C)nc(Cl)c3c2)n1

InChI Key InChIKey=UCXIKENKSBLXSM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 138204   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138204(US8871778, 161)
Affinity DataIC50:  11.1nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138204(US8871778, 161)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138204(US8871778, 161)
Affinity DataIC50:  1.12E+3nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In DepthDetails US Patent