BDBM14083 2-ketobenzothiazole 23::N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]cyclopentanecarboxamide

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6](-[#7]-[#6](=O)-[#6]-1-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-c1nc2ccccc2s1

InChI Key InChIKey=CSXRBLWDXFLMQA-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14083   

TargetSerine protease 1(Bovine)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 14083BDBM14083(N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-o...)
Affinity DataKi:  30nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14083BDBM14083(N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-o...)
Affinity DataKi:  1.23E+4nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14083BDBM14083(N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-o...)
Affinity DataKi:  1.46E+4nM IC50: 8.20E+4nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed