BDBM14250 4-bromo-3-(carboxymethoxy)-5-(4-hydroxyphenyl)thiophene-2-carboxylic acid::Monocyclic thiophene analog 17

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1ccc(O)cc1

InChI Key InChIKey=QZWUMLLRAVGBHC-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14250   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14250(4-bromo-3-(carboxymethoxy)-5-(4-hydroxyphenyl)thio...)
Affinity DataKi:  300nM ΔG°:  -8.80kcal/molepH: 7.0 T: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair