BDBM144851 US8952157, 33::US9303025, 33

SMILES Cc1nc(C)c(s1)-c1cccc(Oc2cc(ccc2C(=O)NS(=O)(=O)c2ccc(NCCCN3CCOCC3)c(c2)[N+]([O-])=O)N2CCN(Cc3ccccc3-c3ccc(Cl)cc3)CC2)c1

InChI Key InChIKey=LXPFXDMUHMUYCP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144851   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM144851(US8952157, 33 | US9303025, 33)
Affinity DataKi:  7.17nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM144851(US8952157, 33 | US9303025, 33)
Affinity DataKi:  7.17nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails US Patent