BDBM145164 US8952157, 355::US9303025, 355

SMILES CC(=O)Nc1ccc(Oc2cc(ccc2C(=O)NS(=O)(=O)c2ccc(NCC3CCOCC3)c(c2)[N+]([O-])=O)N2CCN(CC3=C(CC(C)(C)CC3)c3ccc(Cl)cc3)CC2)cn1

InChI Key InChIKey=KBPOWMBYRCIWQG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145164   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM145164(US8952157, 355 | US9303025, 355)
Affinity DataKi:  9.57nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM145164(US8952157, 355 | US9303025, 355)
Affinity DataKi:  9.57nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails US Patent