BDBM150275 US8987239, A::US9034856, A

SMILES C[C@]12CC[C@H]3[C@@H]([C@H]4C[C@H]4C4=CC(=O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1

InChI Key InChIKey=METQSPRSQINEEU-HXCATZOESA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 150275   

TargetProgesterone receptor(Homo sapiens (Human))
Bayer Intellectual Property Gbmh

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  43.3nMAssay Description:Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
Bayer Intellectual Property Gbmh

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  630nMAssay Description:The test was carried out as in 1, with the following modifications: cytosol from androgen receptor-expressing insect cells (Hi5) was used, and the re...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Bayer Intellectual Property Gbmh

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  43.3nMAssay Description:Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
Bayer Intellectual Property Gbmh

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  630nMAssay Description:Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bayer Intellectual Property Gbmh

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  27nMAssay Description:Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150275(US8987239, A | US9034856, A)
Affinity DataIC50:  3.30nMAssay Description:Using cytosol from progesterone receptor-expressing insect cells (Hi5), competitive binding to the progesterone receptor was determined from the abil...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank