BDBM156566 US10118915, Compound 346::US9682966, 346

SMILES CO[C@@H]1CN(CC[C@@H]1NC1CCCC1)c1nc(C)c(C)cc1-c1nc(C)no1

InChI Key InChIKey=JRJOHFSLNLQIDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156566   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM156566(US9682966, 346 | US10118915, Compound 346)
Affinity DataIC50: 137nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM156566(US9682966, 346 | US10118915, Compound 346)
Affinity DataIC50: 137nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent