BDBM161150 US9051265, 58::US9051265, 98

SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(Cl)c(O[C@@H](C)C(O)=O)c3)c(C)c(C)c2c1)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=NPMSSJHJPGMEJW-UNMCSNQZSA-N

Data  5 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 161150   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM161150(US9051265, 58 | US9051265, 98)
Affinity DataIC50:  0.200nMAssay Description:The assay was performed according to manufacturer protocol. A mixture of 5 nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan- PPAR Green, an...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM161150(US9051265, 58 | US9051265, 98)
Affinity DataIC50:  263nMAssay Description:The assay was performed according to manufacturer protocol. A mixture of 5 nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan- PPAR Green, an...More data for this Ligand-Target Pair
LigandPNGBDBM161150(US9051265, 58 | US9051265, 98)
Affinity DataIC50:  9.00E+3nMAssay Description:Inverse agonist activity at human PPARdelta expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional repression preincubated for...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM161150(US9051265, 58 | US9051265, 98)
Affinity DataIC50:  935nMAssay Description:Agonist activity at human PPARalpha expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional activation preincubated for 6 hrs f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM161150(US9051265, 58 | US9051265, 98)
Affinity DataIC50:  12nMAssay Description:Inverse agonist activity at human PPARgamma expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional repression preincubated for...More data for this Ligand-Target Pair