BDBM16222 CCT077373::N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}amino)ethyl]isoquinoline-5-sulfonamide::N-[2-({2-[(4-chlorophenyl)methoxy]ethyl}amino)ethyl]isoquinoline-5-sulfonamide::compound 1::isoquinoline-5-sulfonamide 9

SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1

InChI Key InChIKey=AUHWQSZMVMMRLM-UHFFFAOYSA-N

Data  6 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 16222   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  260nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  170nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  230nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16222(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Affinity DataIC50:  260nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair