BDBM173694 US9102591, 2,3-dichloro-N-[2-(6-cyclopropyl-3-pyridyl)-3-[1-(difluoromethyl)cyclopropyl]propyl]benzamide::US9649308, 2,3-dichloro-N-[2-(6-cyclopropyl-3-pyridyl)-3-[1-(difluoromethyl)cyclopropyl]propyl]benzamide
SMILES FC(F)C1(CC(CNC(=O)c2cccc(Cl)c2Cl)c2ccc(nc2)C2CC2)CC1
InChI Key InChIKey=OLJZHLVOYTZYEL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 173694
Affinity DataIC50: 0.760nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium mobilization monitored for 5 min...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium mobilization monitored for 5 min...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair