BDBM175821 US9688684, Compound 18: {4-[7-(3-Isopropyl-1-phenyl-1H-pyrazol-4-ylmethyl)-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazin-8-yl]-phenyl}-dimethyl-amine

SMILES CC(C)c1nn(cc1CN1CCn2nnnc2C1c1ccc(cc1)N(C)C)-c1ccccc1

InChI Key InChIKey=UBLDGRAQSOUUAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175821   

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandPNGBDBM175821(US9688684, Compound 18: {4-[7-(3-Isopropyl-1-pheny...)
Affinity DataIC50: 2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent