BDBM17660 (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid::2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid::CHEMBL279956::Quisqualate::Quisqualate, L::quisqualic acid
SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
InChI Key InChIKey=ASNFTDCKZKHJSW-REOHCLBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 61 hits for monomerid = 17660
TargetGlutamate receptor ionotropic, kainate 4(Homo sapiens (Human))
Allelix Biopharmaceuticals
Curated by PDSP Ki Database
Allelix Biopharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 10nMAssay Description:Binding affinity at Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataKi: 55nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataKi: 134nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
Affinity DataKi: 171nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataKi: 1.10E+3nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataKi: 1.67E+3nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre
Curated by PDSP Ki Database
Upr Centre
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research
Curated by PDSP Ki Database
Cns Research
Curated by PDSP Ki Database
Affinity DataKi: 4.00E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 1.12E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataKi: 1.13E+5nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 1.00E+6nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMpH: 7.4 T: 2°CAssay Description:The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: 630nMAssay Description:Agonist activity at mGlu5 receptor (unknown origin) expressed in CHO cells assessed as increase in Gq-mediated PI hydrolysis after 45 mins by yttrium...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre
Curated by PDSP Ki Database
Upr Centre
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in humanMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in humanMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataEC50: >5.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR3 in ratMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair