BDBM180196 US9133157, 78

SMILES COC(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@H](c1ccc(s1)[C@@H](CO)N(C(C)C)S(=O)(=O)c1ccc2[nH]ccc2c1)C(F)(F)F

InChI Key InChIKey=GPAXISAHIUZPKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180196   

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180196(US9133157, 78)
Affinity DataIC50: 66.1nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent