BDBM180267 US9676721, 91 2-cyano-3-(pyridin-4-yl)-1-[(4-{[3-(trifluoromethoxy)benzene]sulfonyl}phenyl)methyl]guanidine

SMILES FC(F)(F)Oc1cccc(c1)S(=O)(=O)c1ccc(CNC(Nc2ccncc2)=NC#N)cc1

InChI Key InChIKey=OSHZYJJYBZWSLR-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180267   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180267(US9676721, 91 2-cyano-3-(pyridin-4-yl)-1-[(4-{[3-(...)
Affinity DataIC50:  6.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB