BDBM18937 2-[3,5-dichloro-4-(3-cyclohexyl-4-hydroxyphenoxy)phenyl]acetic acid::4-hydroxy thyromimetic, 9s

SMILES OC(=O)Cc1cc(Cl)c(Oc2ccc(O)c(c2)C2CCCCC2)c(Cl)c1

InChI Key InChIKey=UTTJYFMWZBKOLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18937   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18937(2-[3,5-dichloro-4-(3-cyclohexyl-4-hydroxyphenoxy)p...)
Affinity DataIC50:  258nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of Insubria

Curated by ChEMBL
LigandPNGBDBM18937(2-[3,5-dichloro-4-(3-cyclohexyl-4-hydroxyphenoxy)p...)
Affinity DataIC50:  7.76nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of Insubria

Curated by ChEMBL
LigandPNGBDBM18937(2-[3,5-dichloro-4-(3-cyclohexyl-4-hydroxyphenoxy)p...)
Affinity DataIC50:  7.70nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed