BDBM192661 2,5-diphenyl-1,3,4-oxadiazole (2a)

SMILES c1ccc(cc1)-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=DCJKUXYSYJBBRD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192661   

TargetCathepsin L(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192661(2,5-diphenyl-1,3,4-oxadiazole (2a))
Affinity DataKi:  124nM ΔG°:  -9.79kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192661(2,5-diphenyl-1,3,4-oxadiazole (2a))
Affinity DataKi:  2.69E+3nM ΔG°:  -7.90kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

LigandPNGBDBM192661(2,5-diphenyl-1,3,4-oxadiazole (2a))
Affinity DataKi:  2.72E+3nM ΔG°:  -7.89kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed