BDBM199303 US9221808, 1bh
SMILES COc1cccc(c1)[C@@H](C)NC(=O)Nc1nc(cs1)-c1ccncc1
InChI Key InChIKey=PZUHTMLHMMXBQW-GFCCVEGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 199303
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 30nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged ROCK1 (1 to 535) (unknown origin) using KKRPQRRSNVF as substrate after 1 hr by Z-Lyte-based FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal GST-tagged ROCK2 (1 to 552) (unknown origin) using KKRPQRRSNVF as substrate after 1 hr by Z-Lyte-based FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair