BDBM201302 US9187424, 224::US9187424, 66

SMILES FC(F)(F)CCCOc1ccc(cc1)C1(CC(=C(C#N)C(=O)N1)c1ccc(cc1)C#N)C(F)(F)F

InChI Key InChIKey=DDFSXUYDYSASSJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 201302   

LigandPNGBDBM201302(US9187424, 224 | US9187424, 66)
Affinity DataIC50: 51nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandPNGBDBM201302(US9187424, 224 | US9187424, 66)
Affinity DataIC50: 231nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandPNGBDBM201302(US9187424, 224 | US9187424, 66)
Affinity DataIC50: 265nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

LigandPNGBDBM201302(US9187424, 224 | US9187424, 66)
Affinity DataIC50: 414nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

LigandPNGBDBM201302(US9187424, 224 | US9187424, 66)
Affinity DataIC50: 731nMpH: 7.4 T: 2°CAssay Description:MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent