BDBM213420 US9278981, 12

SMILES OC1CCN(C1)c1ncc(cc1-c1cncnc1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=LARFZNXVNANWFD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 213420   

TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM213420(US9278981, 12)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB