BDBM215895 US9302989, 91

SMILES O=C(Nc1ccc(cc1)C(=O)NCC1CCOC1)N1Cc2ccccc2C1

InChI Key InChIKey=BLZJCPAXCWJANZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215895   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM215895(US9302989, 91)
Affinity DataKi:  24nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM215895(US9302989, 91)
Affinity DataIC50:  34.2nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB