BDBM222559 US9315491, MTR-0195::US9801888, Compound MTR-0195

SMILES CNC(=O)Nc1ccc(cc1)-c1nc(Cl)c(SC)c(n1)N1CCOCC1

InChI Key InChIKey=JBUJKZTUEXATPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222559   

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222559BDBM222559(US9315491, MTR-0195 | US9801888, Compound MTR-0195)
Affinity DataIC50: 116nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandChemical structure of BindingDB Monomer ID 222559BDBM222559(US9315491, MTR-0195 | US9801888, Compound MTR-0195)
Affinity DataIC50: 116nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent