BDBM237222 1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-3-phenylthiourea (3b)

SMILES COc1ccc(cc1)N(Cc1ccc(O)c(OC)c1)C(=S)Nc1ccccc1

InChI Key InChIKey=KQMLPLCAZCMUMF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237222   

TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237222(1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...)
Affinity DataIC50:  3.21E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237222(1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetETS domain-containing protein Elk-1(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237222(1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...)
Affinity DataIC50:  2.42E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237222(1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...)
Affinity DataIC50:  1.93E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237222(1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed