BDBM24127 (4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide::CHEMBL205786::tetrahydroisoquinoline (THIQ), 32a

SMILES CN(C)C(=O)N1C[C@H](c2cccc(O)c2)c2ccc(C)c(C)c2C1

InChI Key InChIKey=HPVCRUIDFODATB-LJQANCHMSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24127   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24127((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...)
Affinity DataIC50:  104nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24127((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...)
Affinity DataIC50:  104nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24127((4R)-4-(3-hydroxyphenyl)-N,N,7,8-tetramethyl-1,2,3...)
Affinity DataIC50:  306nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair