BDBM24624 CHEMBL272980::MGCD-0103::MGCD0103::N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide::US10227295, Compound MGCD0103::US11377423, MGCD-0103::US9409858, MGCD0103::US9751832, MGCD0103::US9956192, Compound MGCD0103

SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cccnc2)cc1

InChI Key InChIKey=HRNLUBSXIHFDHP-UHFFFAOYSA-N

Data  68 IC50  3 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24624   

TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  102nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  1.00E+4nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails US Patent