BDBM26106 CHEMBL90852::N-oxalyl glycine, 1a::NOG::Oxalylglycine::[(carboxymethyl)carbamoyl]formic acid

SMILES OC(=O)CNC(=O)C(O)=O

InChI Key InChIKey=BIMZLRFONYSTPT-UHFFFAOYSA-N

Data  4 KI  49 IC50  6 Kd

PDB links: 399 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 26106   

TargetLysine-specific demethylase 5D [1-775](Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  5.80E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

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TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  4.15E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  680nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  290nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
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TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  4.59E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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TargetLysine-specific demethylase 5C [1-765](Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  3.50E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  2.45E+4nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
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TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  7.80E+4nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
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TargetLysine-specific demethylase 5A [1-801](Homo sapiens (Human))
University of Oxford

LigandBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Copy SMILESCopy InChI

Affinity DataIC50:  6.90E+3nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
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