BDBM27091 2-phenyl-1H-1,3-benzodiazole-4-carboxamide::CHEMBL81723::phenyl-containing benzimidazole carboxamide, 2b
SMILES NC(=O)c1cccc2nc([nH]c12)-c1ccccc1
InChI Key InChIKey=OBBJGEVEIULNEO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 27091
Affinity DataKi: 15nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 17nM ΔG°: -10.5kcal/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
Affinity DataEC50: 75nMAssay Description:Inhibition of PARP1 in human C41 cells by FITC-conjugated DAPI stainingMore data for this Ligand-Target Pair