BDBM27219 (2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,2-a][1,2,4]triazin-2-yl]amino}butan-1-ol::(2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[2,1-f][1,2,4]triazin-2-yl]amino}butan-1-ol::imidazo[2,1-f]-1,2,4-triazine, 13

SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncc(C(C)C)n2n1

InChI Key InChIKey=ITFLOJJAVYXCTM-OAHLLOKOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 27219   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50:  200nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50:  600nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27219((2R)-2-{[4-(benzylamino)-7-(propan-2-yl)imidazo[1,...)
Affinity DataIC50:  320nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed