BDBM272540 US10065967, Example 6::US10759805, Ex 6::US9745307, Example 6

SMILES Cn1cc(cn1)-c1n[nH]c2cc3[nH]c(=O)c(Br)cc3cc12

InChI Key InChIKey=MNSQBNBSWCBRNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 272540   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272540(US10065967, Example 6 | US10759805, Ex 6 | US97453...)
Affinity DataIC50:  0.300nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272540(US10065967, Example 6 | US10759805, Ex 6 | US97453...)
Affinity DataIC50:  300nMAssay Description:Human: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272540(US10065967, Example 6 | US10759805, Ex 6 | US97453...)
Affinity DataIC50:  0.300nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent