BDBM29029 cyanohydroxybutenamide, 19

SMILES COc1ccccc1-c1ccc(NC(=O)C(C#N)C(C)=O)c(Cl)c1

InChI Key InChIKey=TUFJFMVDXYQLBZ-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29029   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Leeds

LigandPNGBDBM29029(cyanohydroxybutenamide, 19)
Affinity DataKi:  25nM IC50:  200nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM29029(cyanohydroxybutenamide, 19)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.18kcal/mole IC50:  8.60E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed