BDBM312505 5-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6,6-difluoro-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-3,6-dihydro-2H-pyran-4-carboxylic acid::US9604977, Example 251

SMILES OC(=O)C1=C(COCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(no1)C1CC1

InChI Key InChIKey=QAECXAUIHCLYIS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312505   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312505(5-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6,6-dif...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312505(5-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6,6-dif...)
Affinity DataIC50:  183nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB