BDBM31385 CHEMBL281240::terephthalamide scaffold, 17

SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1NC(C)C)C(=O)N(C(C)C)C(C)C)C(O)=O

InChI Key InChIKey=DMEGSOYYABSRKY-FQEVSTJZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31385   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM31385(CHEMBL281240 | terephthalamide scaffold, 17)
Affinity DataKi:  3.31E+3nM ΔG°:  -7.47kcal/molepH: 7.4 T: 2°CAssay Description:Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM31385(CHEMBL281240 | terephthalamide scaffold, 17)
Affinity DataKi:  3.31E+3nMAssay Description:Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed