BDBM319531 N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6-[4-(2- methyl-2H-1,2,3, 4-tetrazol-5-yl) phenyl]-1,3- benzothiazol- 2-yl}-2-(2- methoxyethane- sulfonyl)acetamide::US10173991, Example 593

SMILES COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(F)c(cc2s1)-c1ccc(cc1)-c1nnn(C)n1

InChI Key InChIKey=GJPCPALOXGRZRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319531   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319531(N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6...)
Affinity DataIC50: 9nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent