BDBM327827 (R)-2-(4-benzhydryl-2-methylpiperazin-1-yl)acetic acid::US9663476, Compound 18

SMILES C[C@@H]1CN(CCN1CC(O)=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=YZLHCJXFENMEAB-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327827   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM327827((R)-2-(4-benzhydryl-2-methylpiperazin-1-yl)acetic ...)
Affinity DataIC50:  1.51nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent