BDBM333850 2-methylpropyl (3S)-3-{[8-(1- ethyl-5-methyl-1H-pyrazol-4- yl)-9-methyl-9H-purin-6- yl]oxy}pyrrolidine-1- carboxylate::US9730940, Compound 1-4

SMILES CCn1ncc(c1C)-c1nc2c(OC3CCN(C3)C(=O)OCC(C)C)ncnc2n1C

InChI Key InChIKey=QIBOGAOJGHLTBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333850   

LigandPNGBDBM333850(2-methylpropyl (3S)-3-{[8-(1- ethyl-5-methyl-1H-py...)
Affinity DataIC50: 17nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent