BDBM3457 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(dimethylamino)propyl](methyl)amino}pyrido[2,3-d]pyrimidin-7-yl]urea::6-arylpyrido[2,3-d]pyrimidine deriv. 39

SMILES CN(C)CCCN(C)c1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1

InChI Key InChIKey=KTQXUWCOAYRSAJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3457   

LigandChemical structure of BindingDB Monomer ID 3457BDBM3457(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(dime...)
Affinity DataIC50: 1.10E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3457BDBM3457(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(dime...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3457BDBM3457(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(dime...)
Affinity DataIC50: 1.60E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed