BDBM3459 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-({2-[(dimethylamino)methyl]-2-methylpropyl}amino)pyrido[2,3-d]pyrimidin-7-yl]urea::6-arylpyrido[2,3-d]pyrimidine deriv. 41

SMILES CN(C)CC(C)(C)CNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1

InChI Key InChIKey=NEADWQYKOBKUBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3459   

LigandChemical structure of BindingDB Monomer ID 3459BDBM3459(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-({2-[(dim...)
Affinity DataIC50: 210nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3459BDBM3459(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-({2-[(dim...)
Affinity DataIC50: 3.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3459BDBM3459(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-({2-[(dim...)
Affinity DataIC50: 3.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed