BDBM355647 1-{2-Oxo-2-[(1R,3S,5R)-3-((1R,2S)- 2-phenyl-cyclopropylcarbamoyl)-2- aza-bicyclo[3.1.0]hex-2-yl]-ethyl}- 1H-indazole-3-carboxylic acid amide::US9815819, 12

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@@H]2C[C@H]2c2ccccc2)c2ccccc12

InChI Key InChIKey=RZCSWCSEYQUVRA-APOUVHJUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355647   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355647(1-{2-Oxo-2-[(1R,3S,5R)-3-((1R,2S)- 2-phenyl-cyclop...)
Affinity DataIC50:  60nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent