BDBM356224 N-(2-((1H-imidazol-1- yl)methyl)-4-phenylpyrimidin-5- yl)-3-(1-methyl-1H-pyrazol-3- yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 224

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1cnc(Cn2ccnc2)nc1-c1ccccc1

InChI Key InChIKey=CIQZUYGSTOSJFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356224   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356224(US9815846, Compound 224 | N-(2-((1H-imidazol-1- yl...)
Affinity DataIC50: 1.60nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent