BDBM373097 1-(5-methyl-3- phenylisoxazol-4- yl)-3-[2- (trifluoromethyl) benzyl]urea::US9896447, Compound 14

SMILES Cc1onc(c1NC(=O)NCc1ccccc1C(F)(F)F)-c1ccccc1

InChI Key InChIKey=JOPADRLBMVFGBD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373097   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373097(1-(5-methyl-3- phenylisoxazol-4- yl)-3-[2- (triflu...)
Affinity DataIC50:  350nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB