BDBM3751 Pyrimido[4,5-b]indole deriv. 42::dimethyl(2-{9H-pyrimido[4,5-b]indol-4-ylamino}ethyl)amine

SMILES CN(C)CCNc1ncnc2[nH]c3ccccc3c12

InChI Key InChIKey=XPZFMMISYLFNHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3751   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandChemical structure of BindingDB Monomer ID 3751BDBM3751(dimethyl(2-{9H-pyrimido[4,5-b]indol-4-ylamino}ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed