BDBM383210 US10278929, Compound 1::US11337935, Compound 1

SMILES OC(=O)c1ccc(cc1)-c1c(F)cccc1F

InChI Key InChIKey=CWWIIKLXUPZDOG-UHFFFAOYSA-N

Data  1 Kd  1 ITC

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383210   

TargetTransthyretin(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383210(US10278929, Compound 1 | US11337935, Compound 1)
Affinity DataKd:  72.5nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 383210   

CellTransthyretin(Homo sapiens (Human))
Leland Stanford Junior University

US Patent
SyringePNGBDBM383210(US10278929, Compound 1 | US11337935, Compound 1)
ITC DataΔG°: -9.74kcal/mole −TΔS°: 21.7kcal/mole ΔH°: -31.5kcal/mole logk: 1.41E+7
pH: 7.5 T: 25.00°C