BDBM384850 N-{(R)-cyclopropyl[4- (difluoromethyl)-3- fluorophenyl]methyl}-2- (dimethylamino)-6-oxo-1,6- dihydropyrimidine-4-carboxamide::US10285989, Example 66

SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)N[C@H](C1CC1)c1ccc(C(F)F)c(F)c1

InChI Key InChIKey=FLHZKSBZYGPMSL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384850   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384850(N-{(R)-cyclopropyl[4- (difluoromethyl)-3- fluoroph...)
Affinity DataKi:  5nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
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Date in BDB:
2/27/2020
Entry Details
US Patent