BDBM395546 (R)-1-((2-(2′-chloro-3′-(1,5-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-d]imidazole-2-carboxamido)-2-methylbiphenyl-3-yl)-7-cyanobenzo[d]oxazol-5-yl)methyl)-3-methyl pyrrolidine-3-carboxylic acid::US10308644, Example 158::US10800768, Example 158::US11339149, Example 158

SMILES CN1Cc2nc(C(=O)Nc3cccc(c3Cl)-c3cccc(-c4nc5cc(CN6CC[C@](C)(C6)C(O)=O)cc(C#N)c5o4)c3C)n(C)c2C1

InChI Key InChIKey=DQSFQXDJUKJFCW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395546   

LigandPNGBDBM395546(US10308644, Example 158 | (R)-1-((2-(2′-chlo...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395546(US10308644, Example 158 | (R)-1-((2-(2′-chlo...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395546(US10308644, Example 158 | (R)-1-((2-(2′-chlo...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent