BDBM4171 1,6-naphthyridin-2(1H)-one deriv. 7d::3-(2,6-Dichlorophenyl)-7-[[2-(diethylamino)ethyl]amino]-::3-(2,6-dichlorophenyl)-7-{[2-(diethylamino)ethyl]amino}-1-methyl-1,2-dihydro-1,6-naphthyridin-2-one

SMILES CCN(CC)CCNc1cc2c(cn1)cc(-c1c(Cl)cccc1Cl)c(=O)n2C

InChI Key InChIKey=ABAWTOZNWVBCHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4171   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4171BDBM4171(3-(2,6-Dichlorophenyl)-7-[[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 1.30E+4nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4171BDBM4171(3-(2,6-Dichlorophenyl)-7-[[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 3.30E+4nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4171BDBM4171(3-(2,6-Dichlorophenyl)-7-[[2-(diethylamino)ethyl]a...)
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed