BDBM4194 1,8-Naphthyridin-2(1H)-one deriv. 9a::7-Amino-3-(2,6-dichlorophenyl)-1-methyl-1,8-naphthyridin-2(1H)-one::7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydro-1,8-naphthyridin-2-one

SMILES Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2ccc(N)nc21

InChI Key InChIKey=XGSBUYIMMOCYTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4194   

TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4194BDBM4194(7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydr...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4194BDBM4194(7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydr...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandChemical structure of BindingDB Monomer ID 4194BDBM4194(7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydr...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed